Hongkun Zheng, Founder and CEOIn this dynamic landscape, Biomarker Technologies (BMKGENE) stands as a pioneer of innovation and excellence. Headquartered in Beijing, China, with laboratories and branches in Hong Kong, Singapore, and Germany, the company has been a front-runner in genomics research for over 14 years. Over this journey, it played a crucial role in developing high-throughput sequencing technologies and harnessed the power of bioinformatics to advance the understanding of genetics.
“We offer a diverse range of services, including one-stop genomic research service, intelligent manufacturing, and the BMKCloud bioinformatics analysis platform, which assists researchers in analyzing and interpreting extensive biological data, from microbes and proteins to DNA and RNA. We are committed to advance innovation and empower genomics to improve human health.” says Hongkun Zheng, founder and CEO, BMKGENE.
Among its many groundbreaking offerings is BMKGENE’s spatial transcriptomics technology, which combines imaging, biomarker analysis, sequencing, and bioinformatics to provide a spatially localized view of gene expression within tissue sections. This has profound implications for understanding disease mechanisms, cancer progression, and other elusive biological processes.
Spatial transcriptomics technology was also listed as one of the "top seven technologies to watch in 2022" by the scientific journal Nature. BMKGENE's relentless dedication to innovation and continuous exploration led to the development of another groundbreaking innovation in 2022, namely the microtiter-based subcellular spatial microarray BMKMANU S1000. This is backed by supporting reagents and consumables, which together with BMKGENE's spatial transcriptome sequencing services, allow researchers to obtain a comprehensive subcellular spatial-temporal dynamic expression profile.
BMKGENE is now advancing spatial transcriptomics with a patented technology for cell segmentation. This method blends original fluorescence and hematoxylin and eosin (H&E) staining with high-throughput sequencing to create non-intersecting regions representing individual cells. Sequencing data is then obtained for each region, enhancing the ability to study cell variations in various biological samples.
BMKGENE's commitment to genomics extends to its one-stop platform, BMKCloud, which integrates analysis software, databases, and cloud computing to facilitate efficient data analysis, public data searches, and collaborative research, enabling genomics researchers to readily gain valuable support.
It enables quick and efficient data analysis of high-throughput sequencing data from the initial stages to later stages. Users can also perform searches and integration analyses of relevant public data, including public sequencing data, literature, and functional gene information.
BMKCloud also facilitates the study and exchange of analytical techniques and research ideas, allowing users to conduct large-scale biological data analysis independently and from multiple perspectives. This level of accessibility and sophistication in data analysis is invaluable in genomics.
We offer a diverse range of services, including research, intelligent manufacturing, and the BMKCloud bioinformatics analysis platform, which assists researchers in analyzing and interpreting extensive biological data, from microbes and proteins to DNA and RNA
Together, this diverse group of experts successfully deciphered the rye genome, a milestone in genomics. As the sequencing provider for this project, BMKGENE played a pivotal role, with its R&D actively contributing to the findings as co-authors. The study, "A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes," was published in Nature Genetics.
The results of this groundbreaking research initiative shed new light on the genomic properties of rye and the regulatory genes governing its agronomic traits. The Weining rye genome assembly represents a significant step in understanding rye genome biology, deepening comparative cereal genomics research, and accelerating genetic improvements in related cereal crops. This collaborative effort exemplifies BMKGENE's commitment to advancing genomics and bringing its positive impact to the larger scientific community.
As BMKGENE continues to push the boundaries of what is possible in genomics, it remains a driving force in the quest to unlock the secrets of life itself.
